The Fel d1 allergen is found only in cats and accounts for 60% of allergic reactions to felines. Typical reactions to this allergen vary, but can include symptoms ranging from sneezing, itchy or swollen eyes to hives and severe difficulty breathing. Individuals allergic to cats and not other animals are often allergic only to Fel d1.

Over 12 allergens have been identified in cats, but 11 of these are found in other mammals. Allergies to dogs, hamsters, and horses may be caused by these other allergens also present in cats. Individuals with severe allergies to other animals may have little benefit from a cat low in Fel d1.

Fel d1 is a very small glycoprotein created in the salivary (saliva), sebaceous (skin), and anal glands, and easily becomes airborne during grooming. The allergen is very stable and remains active for months. Production of the allergen is hormonally controlled, with the highest levels found in un-neutered males, and lowest levels are found in neutered females.

Bathing cats with shampoos or solutions containing buffered borate washes off or deactivates the allergens, but normal levels begin to return within a week. Routine washing does reduce the amount of allergen buildup in the home. There are several excellent products that will prevent the allergen from becoming airborne during daily brushing or combing.

In recent years hypoallergenic cats have repeatedly made news headlines. What is “hypoallergenic” where cats are concerned, and what are "reasonable expectations" for allergy sufferers at this time?

Research has shown that all cats produce some Fel d1, but some cats produce considerably less than others.  Breeds are thought to trigger fewer allergies include the Devon Rex, Sphynx, and Siberian. Strong anecdotal evidence exists to support some of these claims, but scientific data is currently lacking.  Recently UC Davis begun researching the hypoallergenic qualities of Siberians.

Siberian Research studies have shown a strong correlation between allergen levels in saliva and perceived allergic reaction. We have been found this trait is genetic and passed on to offspring. SRI is working with breeders to test Siberian allergen levels, and is also working with UC Davis towards uncovering the genes that create low-allergy cats.

You may wish to review strategies that we have developed for allergy testing with Siberian Cats.  The following pages discuss these issues.

• Visiting a Cattery reviews various methods for allergy testing while visiting a Siberian cattery and watching your reactions.
• Testing with Fur is helpful when it is not possible to visit a Siberian Cattery. This page reviews different suggestions for fur testing.

Disclaimer:

Information provided by SRI is intended to be a general summary on the topic provided.

It is not intended to take the place of your own research.

Severe allergies should always be discussed with a medical professional.

Siberian Research, Inc. All Rights Reserved (c) Copyright 2008